2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

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Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-A0199
    Sodium tetradecyl sulfate (27% in water) 139-88-8
    Sodium tetradecyl sulfate (Tergitol 4) is a novel scleroembolic agent and an apoptosis inducer. Sodium tetradecyl sulfate can be used for research on varicose veins and vascular malformation diseases.
    Sodium tetradecyl sulfate (27% in water)
  • HY-A0236
    Aprindine 37640-71-4 98.43%
    Aprindine is an arrhythmia inhibitor that stabilizes the cell membranes of heart muscle cells, thereby preventing abnormal electrical impulses from causing irregular heartbeats. In hematological toxicity studies, aprindine showed potential inhibitory effects on the replicative capacity of mouse and human blood cells at certain concentrations.
    Aprindine
  • HY-B0374
    Moxonidine 75438-57-2 99.72%
    Moxonidine(BDF5895) is a selective agonist at the imidazoline receptor subtype 1, used as antihypertensive agent.
    Moxonidine
  • HY-B0835
    Fenobucarb 3766-81-2 98.30%
    Fenobucarb is a carbamate insecticide. Fenobucarb induces zebrafish developmental neurotoxicity through pathways involved in inflammation, oxidative stress, degeneration and apoptosis. Fenobucarb is a possible risk factor to cardiovascular and cerebrovascular systems in animals.
    Fenobucarb
  • HY-B0918
    Chlorindione 1146-99-2
    Chlorindione (Chlophenadione) is a potent anticoagulant. Chlorindione also is a vitamin K1 antagonist.
    Chlorindione
  • HY-B1264
    Celiprolol hydrochloride 57470-78-7 98.93%
    Celiprolol (REV 5320) is a potent, cardioselective and orally active β1-andrenoceptor r antagonist with partial β2 agonist activity, with Ki values of 0.14-8.3 μM. Celiprolol has antihypertensive and antianginal activity, and can be used for the research of cardiovascular disease such as high blood pressure.
    Celiprolol hydrochloride
  • HY-B1440
    Ethaverine hydrochloride 985-13-7 99.72%
    Ethaverine hydrochloride, a derivative of papaverine, inhibits cardiac L-type calcium channel. Ethaverine hydrochloride is a peripheral vasodilator and antispasmodic agent. Ethaverine hydrochloride can be used for research of peripheral vascular disease.
    Ethaverine hydrochloride
  • HY-B1587
    Carbazochrome 69-81-8 99.94%
    Carbazochrome is a capillary stabiliser and used for the research of haemorrhage. Carbazochrome is an antihemorrhagic agent.
    Carbazochrome
  • HY-B1735
    Picotamide 32828-81-2 99.76%
    Picotamide is a combined inhibitor of thromboxane A2 (TxA2) synthase and receptor. Picotamide has antiplatelet activity. Picotamide promotes the reduction of microalbuminuria and the inhibition of growth of carotid plaques in diabetes. Picotamide can be used for researching acute or chronic cardiovascular diseases.
    Picotamide
  • HY-D1244
    CO probe 1 1043865-37-7 98.3%
    CO probe 1 (probe 2) is a highly efficient fluorescent CO probe (Ex=493 nm) with an allyl ether reaction site. In the presence of PdCl₂, CO reduces Pd2+ to Pd0, triggering a Tsuji-Trost reaction that removes the allyl protecting group, releases fluorescein, and generates a significant fluorescence signal. CO probe 1 has high selectivity, rapid response (fluorescence enhancement of 150 times within 20 minutes), and low cytotoxicity, and can be used for real-time imaging of CO in living cells. CO probe 1 may be used to study pathological mechanisms involving CO signaling regulation, such as inflammation, vascular disease, or cancer.
    CO probe 1
  • HY-N1551
    Przewaquinone A 76843-23-7 98.29%
    Przewaquinone A, a lipophilic diterpene quinone present only in Salvia przewalskii, induces a potent inhibitory action on vascular contraction.
    Przewaquinone A
  • HY-N1974
    Fuziline 80665-72-1 ≥98.0%
    Fuziline is a alkaloid isolated from the lateral roots of Aconitum carmichaelii.
    Fuziline
  • HY-N2005
    Cycleanine 518-94-5 99.80%
    Cycleanine is a potent vascular selective Calcium antagonist. Cycleanine has analgesic, muscle relaxant and anti-inflammatory activities. Cycleanine has potential for anti-ovarian cancer acting through the apoptosis pathway.
    Cycleanine
  • HY-N2107
    Physion 8-O-β-D-glucoside 26296-54-8 ≥98.0%
    Physion 8-O-β-D-glucoside, a bioactive component of Fallopia multiflora, can be used for the research of dizziness.
    Physion 8-O-β-D-glucoside
  • HY-N2115
    Araloside A 7518-22-1 98.31%
    Araloside A (Chikusetsusaponin IV) is a component of Panax japonicus, with low-renin-inhibitory activity, with an IC50 of 77.4 μM.
    Araloside A
  • HY-N2299
    Morusinol 62949-93-3 99.68%
    Morusinol is a flavonoid isolated from Morus alba root bark. Morusinol has an antiplatelet activity and  significantly inhibits arterial thrombosis in vivo.
    Morusinol
  • HY-N2509
    Iristectorigenin B 86849-77-6 99.49%
    Iristectorigenin B (Iristectrigenin B) is a liver X receptor (LXR) modulator. Iristectrigenin B stimulates the transcriptional activity of both LXR-α and LXR-β.
    Iristectorigenin B
  • HY-N2531
    Notoginsenoside Fc 88122-52-5 ≥99.0%
    Notoginsenoside Fc, a protopanaxadiol- (PPD-) type saponin isolated from the leaves of Panax notoginseng, effectively counteracts platelet aggregation. Notoginsenoside Fc can accelerate reendothelialization following vascular injury in diabetic rats by promoting autophagy.
    Notoginsenoside Fc
  • HY-N2929
    β-Hydroxypropiovanillone 2196-18-1
    β-Hydroxypropiovanillone, a natural compound, shows significant concentration-dependent inhibitory effects on α-glucosidase with an IC50 of 257.8 μg/mL.
    β-Hydroxypropiovanillone
  • HY-N3125
    Osajin 482-53-1 98.18%
    Osajin is the major bioactive isoflavone present in the fruit of Maclura pomifera with antitumor, antioxidant and anti-inflammatory activities.
    Osajin
Cat. No. Product Name / Synonyms Application Reactivity